I recently gave two lectures on chip-chip and chip-seq at the Cold Spring Harbor Labs as part of the “Integrative Statistical Analysis of Genome Scale Data” course. During my lectures and labs I have covered various aspects of the analysis of chip data going from raw data to enriched regions and de novo motifs. In [...]
chip-chip and chip-seq course at CSHL
by Raphael Gottardo on 02. Jul, 2010 in Research, Software, Teaching
flowClust free from mclust
by Raphael Gottardo on 19. May, 2010 in News, Research
I just wanted to post a quick note about flowClust. As of version 2.6, flowClust does not depend on mclust anymore. So for those of you who emailed us because you wanted to use flowClust but you found the mclust license too restrictive, you are now free to use flowClust! Because flowClust is distributed under [...]
flowTrans available from Bioconductor
by Raphael Gottardo on 25. Apr, 2010 in Front Page
Greg Finak has just released a Bioconductor/R package for estimating and fitting various transformation to flow cytometry data. The package, flowTrans, has been designed to play well with flowCore and flowClust. This is just a start and we hope to improve the package in the near future, but we wanted to release it ASAP so [...]
ChIP-Seq pipeline: PICS, rGADEM, MotIV
by Raphael Gottardo on 15. Apr, 2010 in News, Research, Software
I thought I would post an update about the status of our ChIP-Seq pipeline, including PICS, rGADEM and MotIV. I know we have promised to release PICS long ago, but we haven’t delivered yet. Well, things have changed today. It is now available on Bioconductor! You can get a copy here. Of course, it is [...]
Congratulations to Marie-Pier and Greg!
by Raphael Gottardo on 09. Nov, 2009 in News, Research
Congratulations to Marie-Pier Scott-Boyer and Greg Finak who have both won a prize in the poster competition at the 2009 Robert-Cedergren colloquium in Bioinformatics. Marie-Pier won the best poster in the PhD category for her work on “Modeling gene expression networks with genomic data to identify determinants of complex quantitative traits in mouse hearts” and [...]
flow cytometry special issue
by Raphael Gottardo on 08. Oct, 2009 in News, Papers, Research, Software
Some of the papers to be published as part of the special issue on bioinformatics approaches to flow cytometry have started to appear online. I expect that all papers accepted will be available soon, including our own paper on flowMerge. If you have not looked at flowMerge yet, please try the R package available from [...]
MonBug symposium
by Raphael Gottardo on 03. Sep, 2009 in General, News, Research
Today is the monbug symposium, and I thought I would send a quick note from the IRCM where it is currently taking place. We have already seen a series of great talks and I can’t wait for the next edition. You can see on this picture, Elaine Mardis, giving the second keynote lecture of the [...]
JSM Talk
by Raphael Gottardo on 10. Aug, 2009 in News, Research
I have received a few emails asking me for my slides of my JSM talk on ChIP-Seq, so I have decided to post them online. You can download the slides here. If you have any questions please do not hesitate to contact me.
flowMerge
by Greg Finak on 05. Jun, 2009 in Research, Software
A new package for improving automated gating of flow cytometry data is now available in BioConductor development release 2.5. flowMerge improves identification of complex cell subpopulations in flowClust models by allowing multiple components to represent the same cell subpopulation. Version 0.3.5 is now in the public repository.
R Journal
by Arnaud Droit on 29. May, 2009 in General, News, Software
The first issue of The R Journal is now available: http://journal.r-project.org
Contact Information
1100 Fairview Avenue North, M2-C200
PO Box 19024
Seattle, WA 98109-1024
Phone: 206-667-4076
Fax: 206-667-4378
Email: rgottard AT fhcrc.org
Search
- PICS: Probabilistic Inference for ChIP-Seq 20. Mar, 2009
- rGADEM soon to support Grand Central Dispatch 17. Apr, 2010
- ChIP-Seq pipeline: PICS, rGADEM, MotIV 15. Apr, 2010
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Open positions
26. Aug, 2010
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The rglab at the FHCRC
24. Aug, 2010
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Welcome to the rglab!
24. Aug, 2010
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Raphael Gottardo: Hello Paolo, Thanks for your comments. I am glad ...
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Paolo: Thanks so much Dr. Gottardo! I'm a happy user of y...
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Raphael Gottardo: Hi Sek, There is a hard coded number of sequences...

